The solution for pain
Pain affects 1 in 5 adults worldwide, outnumbering the patients affected by heart diseases, diabetes and cancer combined. When insufficiently managed, pain can severely limit one’s daily activity. It also has a great impact on one’s quality of life; not only affecting the patient personally, but also their family and professional life.
Recent scientific and clinical evidence has shown that topical pain treatment is effective and safe. In a randomised, double-blind clinical study in the United States, patients with neuropathic pain who were treated with a variety of Active Pharmaceutical Ingredients (APIs) experienced significantly greater pain reduction. Those patients also reported better outcomes regarding walking ability and performance of normal work compared to the placebo group. No serious adverse events were observed.
Topical pain treatment uses cutaneous delivery of APIs to specifically target the soft tissues and peripheral nerves underlying the site of application. Multiple APIs can be combined into a single preparation, offering the possibility for a customised and multimodal approach to achieve additive treatment effects.
Fagron has developed a unique, easy-to-use therapeutic approach that facilitates personalised prescriptions, tailored to the patient’s specific needs.
Topical treatment can relieve pain and enhance physical function and quality of life. Using this route of administration, a wide range of APIs can be applied locally. This offers several benefits:
- Direct delivery to the site of origin of the pain
- Minimal systemic absorption
- Combining different mechanisms of action
- Add-on therapy to oral treatment
Shop Fagron’s pain management range
Fagron and Humco have developed a range of compounding vehicles to achieve optimal therapeutic results in pain management. These vehicles have excellent compatibility with a broad range of APIs, while improving patient comfort and compliance.
An elegant cream base with a unique formulation, Versatile™ retains its consistency with a broad range and high concentration of APIs.
A state-of-the art cream base specifically designed for use in topical pain treatment. SaltStable LS Advanced™ is an extremely durable and robust transdermal cream base formulated with a silogel, that provides a smooth, silky feel.
A transdermal vehicle specially formulated to maintain stability in the presence of high API percentages, solvents, salts and across a wide pH range.